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高磊
研究生培养
培养硕士生6人，博士研究生6人。1人被评为北京协和医学院优秀毕业生，1人被评为北京市优秀毕业生。
个人简介
中国医学科学院/北京协和医学院病原生物学研究所副所长，课题组长。主要从事传染病流行病学研究，重点探索适宜中国结核病高负担国情的结核潜伏感染人群预防干预新技术和新方案。入选教育部新世纪优秀人才、北京市科技新星、协和新星等。国家传染病标准专业委员会委员、中国防痨协会结核潜伏感染防治专业分会副主任委员、中国防痨协会标准化专业分会秘书长、第一批国家健康科普专家库成员。中华结核和呼吸杂志、中国防痨杂志、BMC Infectious Diseases、PLOS Global Public Health、Chronic Diseases and Translational Medicine等学术期刊编委。作为第一作者或通讯作者在Lancet Infect Diseases，European Respiratory Journal等国际学术期刊发表SCI论文50余篇。获中华预防医学会科学技术一等奖、中国防痨协会科学技术一等奖、中华医学科学技术二等奖、高等学校科学研究优秀成果奖自然科学类二等奖、中国医学科学院“杰出贡献奖”、中国医学科学院-法国梅里埃研究院“青年科学家奖”等。
研究方向
结核病等重大传染病的流行病学和精准干预研究
科研项目
1、传染病防治科技重大项目，2017ZX10201302-009，结核潜伏感染干预治疗效果研究 ，子课题负责人
2、传染病防治科技重大项目，2017ZX10201302-00，肺结核人工智能影像诊断系统的优化升级，子课题负责人
3、中国医学科学院医学与健康科技创新工程，2019-I2M-2-005，农村中老年人群结核潜伏感染流行病学调查和干预研究队列，课题负责人
4、传染病防治科技重大项目，2017ZX10201302002，既往肺结核患者潜伏感染干预手段研究，子课题负责人
研究成果
1、Gao L, Lu W, Bai L, Wang X, Xu J, Catanzaro A, Cárdenas V, Li X, Yang Y, Du J, Sui H, Xia Y, Li M, Feng B, Li Z, Xin H, Zhao R, Liu J, Pan S, Shen F, He J, Yang S, Si H, Wang Y, Xu Z, Tan Y, Chen T, Xu W, Peng H, Wang Z, Zhu T, Zhou F, Liu H, Zhao Y, Cheng S, Jin Q; LATENTTB-NSTM study team. Latent tuberculosis infection in rural China: baseline results of a population-based, multicentre, prospective cohort study. Lancet Infect Dis. 2015 Mar;15(3):310-9.
2、Gao L, Li X, Liu J, Wang X, Lu W, Bai L, Xin H, Zhang H, Li H, Zhang Z, Ma Y, Li M, Feng B, Du J, Sui H, Zhao R, Su H, Pan S, Guan L, Shen F, He J, Yang S, Si H, Cheng X, Xu Z, Tan Y, Chen T, Xu W, Peng H, Wang Z, Zhu T, Chen X, Zhou X, Guan X, Jin Q; LATENTTB-NSTM study team. Incidence of active tuberculosis in individuals with latent tuberculosis infection in rural China: follow-up results of a population-based, multicentre, prospective cohort study. Lancet Infect Dis. 2017 Oct;17(10):1053-1061.
3、Zhang H, Xin H, Li X, Li H, Li M, Feng B, Gao L*. Reversion of QuantiFERON-TB Gold In-Tube test in individuals with and without prophylactic treatment for latent tuberculosis infection: A systematic review and meta-analysis. J Infect. 2018 Oct;77(4):276-282.
4、Zhang H, Xin H, Wang D, Pan S, Liu Z, Cao X, Wang J, Li X, Feng B, Li M, Yang Q, Zhang M, Jin Q, Gao L*. Serial testing of mycobacterium tuberculosis infection in Chinese village doctors by QuantiFERON-TB Gold Plus, QuantiFERON-TB Gold In-Tube and T-SPOT.TB. J Infect. 2019;78(4):305-10.
5、Xin H, Zhang H, Cao X, Li X, Li M, Feng B, Jin Q, Gao L*. Serum level of IL-8 is associated with reversion of QuantiFERON-TB gold in-tube tests. J Infect. 2019 Apr;78(4):292-298.
6、Gao L*, Bai L, Liu J, Lu W, Wang X, Li X, Du J, Chen X, Zhang H, Xin H, Sui H, Li H, Su H, He J, Pan S, Peng H, Xu Z, Catanzaro A, Evans TG, Zhang Z, Ma Y, Li M, Feng B, Li Z, Guan L, Shen F, Wang Z, Zhu T, Yang S, Si H, Wang Y, Tan Y, Chen T, Chen C, Xia Y, Cheng S, Xu W, Jin Q*; LATENTTB-NSTM study team. Annual risk of tuberculosis infection in rural China: a population-based prospective study. Eur Respir J. 2016;48(1):168-78.
7、Gao L*, Zhang H, Xin H, Liu J, Pan S, Li X, Guan L, Shen F, Liu Z, Wang D, Guan X, Yan J, Li H, Feng B, Cao X, Chen Y, Cui W, Zhang Z, Ma Y, Chen X, Zhou X, Jin Q*; LATENTTB-NSTM study team. Short-course regimens of rifapentine plus isoniazid to treat latent tuberculosis infection in older Chinese patients: a randomised controlled study. Eur Respir J. 2018 Dec 20;52(6):1801470.
8、Xin H, Cao X, Zhang H, Feng B, Du Y, Zhang B, Wang D, Liu Z, Guan L, Shen F, Guan X, Yan J, He Y, He Y, Quan Z, Pan S, Liu J, Jin Q, Gao L*. Protective efficacy of 6-week regimen for latent tuberculosis infection treatment in rural China: 5-year follow-up of a randomised controlled trial. Eur Respir J. 2022 Jul 7;60(1):2102359.
9、Xin H, Cao X, Zhang H, Liu J, Pan S, Li X, Guan L, Shen F, Liu Z, Wang D, Guan X, Yan J, Li H, Feng B, Zhang M, Yang Q, Jin Q, Gao L*; LATENTTB-NSTM study team. Dynamic changes of interferon gamma release assay results with latent tuberculosis infection treatment. Clin Microbiol Infect. 2020;26(11):p1555.e1-7.
10、Xin H, Zhang H, Liu J, Pan S, Li X, Cao X, Feng B, Guan L, Shen F, Liu Z, Wang D, Yan J, Zhang M, Yang Q, Jin Q, Gao L*. Tuberculosis infection among the elderly in 20,486 rural residents aged 50-70 years old in Zhongmu County, China. Clin Microbiol Infect. 2019;25(9):1120-6.
11、Zhang H, Xin H, Du Y, Cao X, Pan S, Liu J, Guan L, Shen F, Liu Z, Zhang B, Wang D, Feng B, Du J, Guan X, He Y, He Y, Zhang Z, Yan J, Jin Q, Gao L*; LATENTTB TRIAL2-NSTM study team. Tuberculosis preventive treatment among individuals with inactive tuberculosis suggested by untreated radiographic abnormalities: a community-based randomized controlled trial. Emerg Microbes Infect. 2023 Dec;12(1):e2169195.
12、Xin H, Zhang H, Yang S, Liu J, Lu Wei, Bai L, Cao X, Feng B, Jin Q, Gao L*. 5-year follow-up of active tuberculosis development from latent infection in rural China. Clin Infect Dis. 2020;70(5):947-50.
13、Li H, Xin H, Qian S, Li X, Zhang H, Li M, Feng B, Jin Q, Gao L*. The testing of tuberculosis infection among the adolescents born after booster Bacillus Calmette-Guérin vaccination was terminated in China: Subgroup analysis of a population-based cross-sectional study. Front Med. 2017;11(4):528-535.
14、Li X, Yang Y, Liu J, Zhou F, Cui W, Guan L, Shen F, Gao C, Li M, Jin Q*, Gao L*. Treatment outcomes of pulmonary tuberculosis in the past decade in the mainland of China: a meta-analysis. Front Med. 2013;7(3):354-66.
15、He Y, Cao X, Guo T, He Y, Du Y, Zhang H, Feng B, Du J, Zhang B, Wang K, Yan J, Wang D, Liu Z, Pan S, Xin H*, Gao L*. Serial testing of latent tuberculosis infection in patients with diabetes mellitus using interferon-gamma release assay, tuberculin skin test, and creation tuberculin skin test. Front. Public Health. 2022. 10:1025550.